High Quality PT-141 32780-32-8 Peptide for Sexual Dysfunction

Model NO.: API


Customized: Customized


Suitable for: Adult


Purity: >98%


Color: White


Type: Vitamins, Amino Acids and Coenzyme


Packaging Details: 2mg/Vial 1mg/Vial


Specification: 2mg/vial


HS Code: 2901291000




Powder: Yes


Certification: GMP, HSE, ISO 9001, USP, BP


State: Solid


Appearence: White Powder


Grade: Medicine Grade


Application: Used


Trademark: Filter


Origin: Shang Hai



High quality PT-141 32780-32-8 Peptide for sexual dysfunction


















Product Description







Description

PT-141 (Bremelanotide) is a highly potent synthetic peptide analogue of α-MSH that may elicit aphrodisiac effects through stimulation of melanocortin receptors. PT-141 (Bremelanotide) consists of seven amino acids and is a cyclic, shortened lactam variant of alpha-Melanocyte-stimulating hormone (α-MSH), a multifunctional peptide that regulates a broad array of physiological functions. In studies, bremelanotide was shown to induce lordosis in an animal model and was also effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).





Specification

Name: PT-141

Synonyms: Bremelanotide, PT-141 Acetate

CAS #: 189691-06-3

Molecular Formula: C50H68N14O10

Molecular Mass: 1025.2 Da (g/mol)

Amino Acid Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH






Purity

PT-141 has a peptide purity level that exceeds 99.0% as determined by HPLC and MS. This peptide was synthesized with no additives and is supplied as a white lyophilized (freeze-dried) powder.






Usage

Bremelanotide, similarly to its analogues α-MSH and melanotan II, acts as a non-selective agonist of all of the melanocortin receptors except MC2, where it lacks significant affinity. Reported activity of the drug is as follows:

MC1 (Ki = 0.68 nM)

MC2 (Ki > 1000 nM)

MC3 (Ki = 72.07 nM)

MC4 (Ki = 19.25 nM)

MC5 (Ki = 166.8 nM)



Bremelanotide appears to stimulate sexual desire and arousal completely or mostly via activation of the MC4 receptor (the MC3 receptor may also be involved). It modulates inflammation and limits ischemia via activation of the MC1 and MC4 receptors.



According to Palatin Technologies' original 2003 patent for bremelanotide, it possesses approximately 50 times the potency of melanotan II as an inducer of erection in male rats. In addition, it was stated in the patent that the therapeutic window of bremelanotide in animals (specifically, the range of induction of the desired sexual arousal relative to the induction of side effects including nausea, yawning, stretching, and decreased appetite) was >1,000-fold, whereas that of melanotan II was only 3- to 4-fold. They concluded that bremelanotide would be more tolerable than melanotan II.


Related products

1	Abarelix Acetate	98%	183552-38-7
2	Alarelin Acetate	98%	79561-22-1
3	Angiotensin Acetate	98%	58-49-1
4	Angiotensin II	98%	68521-88-0
5	Antide Acetate	98%	112568-12-4
6	Argpressin Acetate	98%	113-79-1
7	Argreline Acetate	98%	616204-22-9
8	Atosiban Acetate	98%	90779-69-4
9	Aviptadil Acetate	98%	40077-57-4
10	Bate-Amyloid(1-42)human	95%	107761-42-2
11	Bivalirudin Trifluoroacetate	98%	128270-60-0
12	Buserelin acetate	98%	57982-77-1
13	Calcuitonin		9007/12/9
14	Carbetocin Acetate	98%	37025-55-1
15	Carperitide	98%	89213-87-6
16	Cerropin B	98%
17	Cetrorelix Acetate	98%	130143-01-0
18	Cetrorelix Acetate	98%	130143-01-0
19	CJC-1295	98%	863288-34-0
20	Copper Peptide(GHK-Cu)	98%	49557-75-7
21	CRF (human, rat) Acetate	98%	86784-80-7
22	CRF (ovine) Trifluoroacetate	98%	79804-71-0
23	Deslorelin Acetate	98%	57773-65-6
24	Desmopressin Acetate	98%	16679-58-6
25	Dynorphin A (1-13) Acetate	98%	72957-38-1
26	Elcatonin Acetate	98%	60731-46-6
27	Eledoisin Acetate	98%	69-25-0
28	Endothelin-1 Acetate	98%	117399-94-7
29	Enfuvirtide Acetate (T-20)	95%	159519-65-0
30	Eptifibatide Acetate	98%	148031-34-9/188627-80-7
31	Exenatide Acetate	98%	141732-76-5
32	Felypressin Acetate	98%	56-59-7
33	Fertirelin Acetate	98%	38234-21-8
34	Ganirelix Acetate	98%	123246-29-7
35	GHRP-2 Acetate	98%	158861-67-7
36	GHRP-6 Acetate	98%	87616-84-0
37	Glatiramer Acetate	99%	147245-92-9
38	GLP(7-36)	98%	107444-51-9
39	GLP-1 (7-37) Acetate	98%	106612-94-6
40	Glucagon Hydrochloride	98%	16941-32-5
41	Gonadorelin Acetate	98%	34973-08-5
42	Goserelin Acetate	98%	145781-92-6
43	GRF (human) Acetate	98%	83930-13-6
44	Hexarelin Acetate	98%	140703-51-1
45	Histrelin Acetate	98%	76712-82-8
46	Icatibant Acetate	98%	30308-48-4
47	Lanreotide	98%	108736-35-2
48	Lecirelin (Dalmarelin) Acetate	98%	61012-19-9
49	Leuprolide	98%	74381-53-6
50	Leuprorelin Acetate	98%	53714-56-0
51	Linaclotide Acatate	98%	851199-59-2
52	Lixisenatide	98%	320367-13-3
53	Lraglutide	98%	204656-20-2
54	Lysipressin Acetate	98%	50-57-7
55	Melanotan II Acetate	98%	121062-08-6
56	MOG(35-55)	98%	163913-87-9
57	Nafarelin Acetate	98%	76932-56-4
58	Nesiritide Acetate (BNP-32)	98%	114471-18-0
59	Octreotide	98%	79517-01-4
60	Ornipressin Acetate	98%	3397-23-7
61	Oxytocin Acetate	98%	50-56-6
62	Palmitoyl Pentapeptide	98%	214047-00-4
63	Pexiganan	98%	147664-63-9
64	Pramlintide Acetate	98%	196078-30-5
65	Pretirelin
66	PT141 Acetate	98%	32780-32-8
67	Salmon Calcitonin Acetate	98%	47931-85-1
68	Secretin Acetate	98%	10813-74-8
69	Sermorelin Aceta	98%	86168-78-7
70	Sincalide	98%	25126-32-3
71	Somatostatin Acetate	98%	38916-34-6
72	Splenopentin Acetate	98%	105184-37-0
73	Taltirelin Acetate	98%	103300-74-9
74	Teriparatide Acetate	98%	52232-67-4
75	Teriparatide Acetate	98%	52232-67-4
76	Terlipressin Acetate	98%	14636-12-5
77	Tetracosactide Acetate	98%	16960-16-0
78	Thymalfasin	98%	62304-98-7
79	Thymopentin	98%	69558-55-0
80	Thymosin α1 Acetate	98%	14636-12-5
81	Thymosin β4 Acetate	98%	77591-33-4
82	Triptorelin Acetate	98%	57773-63-4
83	Vapreotide Acetate	98%	103222-11-3
84	Vasopressin Acetate	98%	9034-50-8
85	Ziconotide Acetate	98%	107452-89-1

Contact us if you need more details on Peptide. We are ready to answer your questions on packaging, logistics, certification or any other aspects about Pharmaceutical Intermediate、Amino Acid. If these products fail to match your need, please contact us and we would like to provide relevant information.

Product Categories : Custom-Made Peptides