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CAS 2627-69-2 AICAR  Acadesine

CAS 2627-69-2 AICAR Acadesine

    Payment Type: L/C,T/T,Paypal
    Terms of Trade: FOB,CIF
    Min. Order: 10 Gram
    Delivery Time: 7 Days
    Packaging:  10g 100g 1kg
    Productivity: 100kg/month
    Brand: cy
    Transportation: Ocean,Land,Air
    Place of Origin: China
    Supply Ability: 50 KG
    Certificate: ISO 9001
    Port: QINGDAO,SHANGHAI

Basic Info

Model No.: CAS 2627-69-2

Product Description



CAS 2627-69-2 AICAR

Product Name:AICAR,Acadesine
Chemical Name:5-Aminoimidazole-4-carboxamide ribonucleotide
CAS NO.:2627-69-2
Molecular Formula:C9H14N4O5
Molecular Weight:258.231
Purity:99%
Appearance:White Powder
Grade:Pharmaceutical Grade

Fat Loss

AICAR is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation. The most important mechanism that AICAR is known for is its ability to block enzymes both in intracellular and extracellular levels, which, in turn, allows for an accelerated stimulation of glucose uptake and increase protein kinases in skeletal muscle tissue. These two functions allow for more energy conversion, which helps burn fat and also sustain output in activity. This is what scientists and athletes/bodybuilders are interested in.

AMP-activated Protein Kinase

AICAR`s principal mechanism of action is activation of AMPK (AMP-activated protein kinase.) Activating AMPK, therefore, causes the same cellular machinery (so to speak) to be turned on as if the cell were energy deprived, for example from intensive exercise, or from low caloric intake.

AICAR, at sufficient and quite substantial concentration, is effective at activating AMPK and inducing a cellular state as if exercise had been performed, or energy stores were low and fat therefore needed to be burned.

AICAR uses metabolic pathways to block certain enzymes, which allows for AMP-activated protein kinase. This can be explained to the layperson like this: once you take a substantial amount of AICAR, it tricks your body at a cellular level in to thinking that exercise has just been preformed. Since the body thinks it has just done a considerable amount of exercise, the energy cycle at the cellular level starts converting fuel sources, like fatty acids, to output the energy that was thought to have been spent during exercise. This can have a direct effect on the level of endurance activity and the sustainability of that activity. Insulin sensitivity is also noted to be one action that AICAR produces, as the body will think it just went through a series of exercises. Interestingly, in animal studies with obese mice, AICAR showed all of the peptides benefits for obese diet induced mice, yet the healthy lean mice did not reap any of the benefits of insulin sensitivity or increase in glucose uptake. That being said, the application in bodybuilding does not seem very suitable, as these mechanisms are targeted for the out-of-shape and over-weight.

Protect against ischemic Injury

Interestingly, AICAR has been shown to protect against ischemic injury. This type of injury is directly related to the restriction of blood to tissues, which can cause insufficient amounts of oxygen and glucose needed to keep the tissue alive. This can lead to thrombosis, embolisms, and vasoconstriction. AICAR can be used as a stabilizing peptide for ischemic episodes, and it can allow for proper blood flow to the myocardium (heart). This function is very interesting, as AICAR could be fundamentally used to treat the heart muscle in the aftermath of a heart attack. This might reduce the possibility for ischemic injuries. Abnormal growths of heart tissues and heart valve function have also been altered in animal studies that used the peptide AICAR, which is a downside.

Shandong Chenyi Environmental Protection Technology Co.,Ltd

 

Shandong Chen Yi environmental protection technology Co., Ltd is a professional chemical products, pharmaceutical intermediates, pharmaceutical raw materials research and development, production and import and export trade enterprises, enterprise leaders have six years of experience in the chemical industry, R & D engineers in large pharmaceutical enterprises for 10 years. The company has cooperated with Shanghai Weiju Industrial Co., Ltd., Qilu University of Technology, Yanggu Liaoyuan Chemical Co., Ltd. and Shandong Confucius Pharmaceutical Co., Ltd. to establish the enterprise's R&D, production and sales system. The company's long-term stable supply of products include more than 30 categories of organic intermediates, pharmaceutical raw materials, additives, plant extracts, catalyst promoters, organic raw materials, dyes, pigments, flavors and fragrances, mainly including maltol, ribonucleic acid, amino acids, anti-cancer drug intermediates, anti-epileptic drug intermediates, API and some Pharmaceutical accessories, and more than 200 kinds of products. Since its inception, adhering to the "integrity, pragmatic, efficient and innovative" spirit of enterprise, integrity management, law-abiding operation, with the most competitive price, to provide you with higher quality products.

We look forward to establishing good cooperation with you.

We supply different kinds of products. High quality and favorable price. We're pleased to get your Inquiry and we will reply you as soon as possible. We stick to the principle of " Quality first, service first, continuous improvement and innovation to meet the customers" For the management and " Zero defect, zero complaints" As the quality objective.




Company Info

  • Company Name: Shandong Chenyi Environmental Protection Technology Co.,Ltd
  • Representative: LIU YA DONG
  • Product/Service: Pharmaceutical Intermediate , API , Food Additive , Maltol , Organic Raw Material , Organic Intermediate
  • Capital (Million US $): 800,000
  • Year Established: 2017
  • Total Annual Sales Volume (Million US $): US$5 Million - US$10 Million
  • Export Percentage: 91% - 100%
  • Total Annual Purchase Volume (Million US $): US$5 Million - US$10 Million
  • No. of Production Lines: 8
  • No. of R&D Staff: 11 -20 People
  • No. of QC Staff: 5 -10 People
  • OEM Services Provided: yes
  • Factory Size (Sq.meters): 1,000-3,000 square meters
  • Factory Location: Yanggu County, Liaocheng City, Shandong Province
  • Contact Person: Mr. Jerry
  • Tel: 86-0531-18560179988
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