Pharmaceutical Intermediate Peptide Carbetocin Acetate CAS: 37025-55-1 with High Quality

Model NO.: 37025-55-1 Customized: Customized Suitable for: Adult Purity: >98% Form: Powder Packing: Vial Other Name: Carbetocin Shelf Life: 2 Years Specification: 10 mg/vial Powder: Yes Certification: GMP State: Solid Name: Carbetocin Acetate Color: White Appearance: White Powder Type: API Trademark: Filter Origin: Shanghai Lab Supply Pharmaceutical Peptide Carbetocin Acetate

Carbetocin Acetate   :
  

CAS:	37025-55-1
MF:	C45H69N11O12S
MW:	988.17
Usage		An obstetric drug used to control postpartum hemorrhaging

Description :
      Carbetocin (INN, BAN) (brand names Duratocin, Pabal, Lonactene, Depotocin, Comoton, Decomoton), or 1-butanoic acid-2-(O-methy-L-tyrosine)-1-carbaoxytocin, is an oxytocic used in obstetrics to control postpartum hemorrhage and bleeding after giving birth, particularly following Cesarean section. It is an eight Amino Acid long analogue of oxytocin (a nonapeptide) and, in accordance, has a similar action. Carbetocin primarily agonizes peripherally expressed oxytocin receptors.

Medicine Use :
     Carbetocin works as an oxytocic, antihemorrhagic and uterotonic drug in the peripheral nervous system. The most common causes of postpartum hemorrhage are lack of tone in the uterus from overstretching or the use of an anesthetic.
     Carbetocin has been approved for use immediately following an elective Cesarean section when a local or spinal anesthesia has been administered.[8] Since the uterus cannot contract on its own following incision during a Cesarean section, exogenous administration of oxytocin or an analog is necessary to restore uterine tone and prevent hemorrhage.
     Safety of carbetocin following vaginal births and emergency Cesarean sections has not been established, though studies have suggested efficacy following vaginal births to that following Cesarean sections. Some studies have shown that a 10-70 ug dose following vaginal delivery caused contractions and no adverse side effects.  
    Carbetocin has also been shown to increase uterine involution (the return of the uterus to its contracted state after the birth of the baby) in humans, horses and cows.  
    Carbetocin has also been shown to stimulate milk letdown through its action on the oxytocin receptors on the myoepithelial cells and there was not a significant amount of carbetocin in breastmilk.[10]
Each dose of Duratocin contains 100 micrograms of carbetocin, 9 mg sodium chloride and ascetic acid. pH is 3.8 and peptide content is greater than 85 percent.

Company Information :
   Our filter biotechnology co.,Ltd is a High-Tech Bio- Chemical Enterprise which is integrated by Professional Scientific R&D, Mass production and sales.As a world-leading provider of Peptide Reagents,Generic Peptide and Custom Peptide Synthesis Services,it has been faithfully serving the Biotech and Pharmaceutical Industries,as well as life science research institutes,Universities and Medical Cosmetology Organization worldwide.
With the linking Enterprise Quality Assurance Agents and conscientious Quality Standard Audit Systems,it could guarantee the Good Quality in the Production Process and on the Finished goods.
Insisting on Faith,Mutual Beneficial Cooperation and Professional,conscientious and efficient work practices, filter biotech has combined the Excellent Inner Techniques and External Resources,fully respects on Clients requirements and actively offers High Standard,Personalized and Professional Services to domestic and overseas clients around the world.
 

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