Pharmaceutical Intermediate Powder Tesamorelin for Treatment of HIV-Associated Lipodystrophy
Basic Info
Model No.: 106612-94-6
Product Description
Model NO.: 106612-94-6 Customized: Customized Suitable for: Lab Research Purity: >98% Application: Pharmaceutical Appearance: Lyophilized Powder Treatment: HIV-Associated Lipodystrophy Specification: iu, mg, g, kg HS Code: 3004905910 Powder: Yes Certification: GMP State: Solid Product Name: Dsip Color: White CAS: 106612-94-6 Trademark: Filter Origin: Shanghai Pharmaceutical Intermediate Powder Tesamorelin for Treatment of HIV-associated Lipodystrophy
Description
Tesamorelin, (formerly known as TH9507), is a type of peptide called a growth hormone-releasing factor (GHRF). GHRF causes growth hormone to be created and spread in the body, which helps increase metabolism, reduce belly fat, improve body shape, and use of energy. Tesamorelin (formerly known as TH9507) is a synthetic growth hormone-releasing factor that stimulates the pituitary gland in the brain to secrete growth hormone; this indirect approach appears to maintain more stable, natural levels, like CJC-1295 DAC,. Clinical trials have shown that tesamorelin significantly reduces abdominal fat with fewer side effects than human growth hormone itself, although abdominal fat may return after the Tesamorlein is discontinued (depending upon the individual). Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals as well as similarly reducing abdominal fat in NON-HIV-Infected individuals.
Specification
Name: Tesamorelin
Synonyms: Hex-hGRF, ThGRF(1-44), TH-9507, (Hexenoyl trans-3)-hGRF(1-44)-NH2
CAS No.: 901758-09-6
Molecular Formula: C221H366N72O67S
Molecular Mass: 5135.78 Da (g/mol)
Amino Acid Sequence: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Purity
Tesamorelin has a peptide purity level that exceeds 99.0% as determined by HPLC and MS.
Usage
Tesamorelin is a stabilized analogue of the growth hormone-releasing factor (GRF) that induces growth hormone (GH) in a specific and physiological manner. To date, clinical studies suggest that Tesamorelin reduces visceral fat in HIV-infected patients with abdominal lipo-hypertrophy as well as reducing abdominal fat in all individuals studied.
A peptide that increases growth hormone release improved several measures of cognitive function in cognitively normal and mildly impaired older individuals in a placebo-controlled trial, a researcher said here. Scores on standard tests of executive function and verbal memory were significantly higher in participants given tesamorelin (Egrifta), a synthetic analog of growth hormone releasing hormone (GHRH), in a 20-week trial, according to Laura D. Baker, PhD.. Participants taking the drug in the 78-person trial also reported greater subjective improvement in cognition relative to the placebo group.
In animal studies, GHRH administration improved biomarkers of brain function as well as performance on cognition tests. And a 2006 clinical trial with GHRH found small but significant improvements in cognitive test scores in healthy older adults. In the current study, funded by the National Institute on Aging, 41 cognitively normal adults and 37 with mild cognitive impairment were randomized to placebo or tesamorelin at 1 mg/day subcutaneously.
Mean participant age was 66 to 70 among the four groups. Scores on the Mini-Mental State Examination averaged 29 for the normal participants and 28 for those with mild impairments. Normal and impaired participants differed more at baseline on a test of story recall, with mean scores of 54 and 44, respectively. Tesamorelin appeared to have a protective effect relative to placebo among the cognitively impaired patients on this measure. At the final evaluation, scores declined an average of five points with placebo, whereas those assigned to tesamorelin had a mean decline of less than one point.
Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals. Lipodystrophy is a condition that causes changes in placement of body fat, including wasting and fat accumulation, and changes in metabolism. Similar to Tesamorelin is Sermorelin, which may be taken with GHRP-6 is clinical trials, that also promotes HGH production and possible fat loss. Individuals with lipodystrophy may develop excess fat most notably around the liver, stomach, and other abdominal organs (visceral body fat).
Our process:
The quality control process
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of producs and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
Our advantages:
1. Quality:
Our company is a professional production of hormone intermediates for many years, our products have exported to Germany,Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, you can trust us.
And we are the manufactory, so no problem for us to control the quality.
2.Payment method: Western Union,TT.
3.Service: Best service with after-sales service to all clients.
4.Delivery:
Sample Order :Package will be shipped with 3days after payment. We can send it via UP, EMS, HK Air Post, DHL or othermethod. We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days.
Other Peptide Our Lab Supply:
Contact us if you need more details on Egrifta. We are ready to answer your questions on packaging, logistics, certification or any other aspects about Tesamorelin、106612-94-6. If these products fail to match your need, please contact us and we would like to provide relevant information.
Description
Tesamorelin, (formerly known as TH9507), is a type of peptide called a growth hormone-releasing factor (GHRF). GHRF causes growth hormone to be created and spread in the body, which helps increase metabolism, reduce belly fat, improve body shape, and use of energy. Tesamorelin (formerly known as TH9507) is a synthetic growth hormone-releasing factor that stimulates the pituitary gland in the brain to secrete growth hormone; this indirect approach appears to maintain more stable, natural levels, like CJC-1295 DAC,. Clinical trials have shown that tesamorelin significantly reduces abdominal fat with fewer side effects than human growth hormone itself, although abdominal fat may return after the Tesamorlein is discontinued (depending upon the individual). Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals as well as similarly reducing abdominal fat in NON-HIV-Infected individuals.
Specification
Name: Tesamorelin
Synonyms: Hex-hGRF, ThGRF(1-44), TH-9507, (Hexenoyl trans-3)-hGRF(1-44)-NH2
CAS No.: 901758-09-6
Molecular Formula: C221H366N72O67S
Molecular Mass: 5135.78 Da (g/mol)
Amino Acid Sequence: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Purity
Tesamorelin has a peptide purity level that exceeds 99.0% as determined by HPLC and MS.
Usage
Tesamorelin is a stabilized analogue of the growth hormone-releasing factor (GRF) that induces growth hormone (GH) in a specific and physiological manner. To date, clinical studies suggest that Tesamorelin reduces visceral fat in HIV-infected patients with abdominal lipo-hypertrophy as well as reducing abdominal fat in all individuals studied.
A peptide that increases growth hormone release improved several measures of cognitive function in cognitively normal and mildly impaired older individuals in a placebo-controlled trial, a researcher said here. Scores on standard tests of executive function and verbal memory were significantly higher in participants given tesamorelin (Egrifta), a synthetic analog of growth hormone releasing hormone (GHRH), in a 20-week trial, according to Laura D. Baker, PhD.. Participants taking the drug in the 78-person trial also reported greater subjective improvement in cognition relative to the placebo group.
In animal studies, GHRH administration improved biomarkers of brain function as well as performance on cognition tests. And a 2006 clinical trial with GHRH found small but significant improvements in cognitive test scores in healthy older adults. In the current study, funded by the National Institute on Aging, 41 cognitively normal adults and 37 with mild cognitive impairment were randomized to placebo or tesamorelin at 1 mg/day subcutaneously.
Mean participant age was 66 to 70 among the four groups. Scores on the Mini-Mental State Examination averaged 29 for the normal participants and 28 for those with mild impairments. Normal and impaired participants differed more at baseline on a test of story recall, with mean scores of 54 and 44, respectively. Tesamorelin appeared to have a protective effect relative to placebo among the cognitively impaired patients on this measure. At the final evaluation, scores declined an average of five points with placebo, whereas those assigned to tesamorelin had a mean decline of less than one point.
Tesamorelin has been shown to reduce lipodystrophy in HIV-infected individuals. Lipodystrophy is a condition that causes changes in placement of body fat, including wasting and fat accumulation, and changes in metabolism. Similar to Tesamorelin is Sermorelin, which may be taken with GHRP-6 is clinical trials, that also promotes HGH production and possible fat loss. Individuals with lipodystrophy may develop excess fat most notably around the liver, stomach, and other abdominal organs (visceral body fat).
Our process:
The quality control process
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of producs and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
Our advantages:
1. Quality:
Our company is a professional production of hormone intermediates for many years, our products have exported to Germany,Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, you can trust us.
And we are the manufactory, so no problem for us to control the quality.
2.Payment method: Western Union,TT.
3.Service: Best service with after-sales service to all clients.
4.Delivery:
Sample Order :Package will be shipped with 3days after payment. We can send it via UP, EMS, HK Air Post, DHL or othermethod. We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days.
Other Peptide Our Lab Supply:
| Product | Purity | CAS No. |
| Abarelix Acetate | 98% | 183552-38-7 |
| Alarelin Acetate | 98% | 79561-22-1 |
| Angiotensin Acetate | 98% | 58-49-1 |
| Angiotensin II | 98% | 68521-88-0 |
| Antide Acetate | 98% | 112568-12-4 |
| Argpressin Acetate | 98% | 113-79-1 |
| Argreline Acetate | 98% | 616204-22-9 |
| Atosiban Acetate | 98% | 90779-69-4 |
| Aviptadil Acetate | 98% | 40077-57-4 |
| Bate-Amyloid(1-42)human | 95% | 107761-42-2 |
| Bivalirudin Trifluoroacetate | 98% | 128270-60-0 |
| Buserelin acetate | 98% | 57982-77-1 |
| Calcitonin | 9007/12/9 | |
| Carbetocin Acetate | 98% | 37025-55-1 |
| Carperitide | 98% | 89213-87-6 |
| Cecropin B | 98% | |
| Cetrorelix Acetate | 98% | 130143-01-0 |
| Cetrorelix Acetate | 98% | 130143-01-0 |
| CJC-1295 | 98% | 863288-34-0 |
| Copper Peptide(GHK-Cu) | 98% | 49557-75-7 |
| CRF (human, rat) Acetate | 98% | 86784-80-7 |
| CRF (ovine) Trifluoroacetate | 98% | 79804-71-0 |
| Deslorelin Acetate | 98% | 57773-65-6 |
| Desmopressin Acetate | 98% | 16679-58-6 |
| Dynorphin A (1-13) Acetate | 98% | 72957-38-1 |
| Elcatonin Acetate | 98% | 60731-46-6 |
| Eledoisin Acetate | 98% | 69-25-0 |
| Endothelin-1 Acetate | 98% | 117399-94-7 |
| Enfuvirtide Acetate (T-20) | 95% | 159519-65-0 |
| Eptifibatide Acetate | 98% | 148031-34-9/188627-80-7 |
| Exenatide Acetate | 98% | 141732-76-5 |
| Felypressin Acetate | 98% | 56-59-7 |
| Fertirelin Acetate | 98% | 38234-21-8 |
| Ganirelix acetate | 98% | 123246-29-7 |
| GHRP-2 Acetate | 98% | 158861-67-7 |
| GHRP-6 Acetate | 98% | 87616-84-0 |
Product Categories : Pharmaceutical Intermediate
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