GMP Lab Supply Cjc1295 5mg with High Purity

Model NO.: API Customized: Non-Customized Suitable for: Adult Purity: >98% The Purity: 0ver 98% Place of Origin: China Transport Package: Plastic Tube, Vial, Box Origin: Shanghai Powder: Yes Certification: GMP State: Solid Shipping Methods: DHL TNT FedEx EMS Storage: Below _18 Trademark: Filter Specification: 5MG/vial HS Code: 2801100000 Pharmaceutical peptide CJC-1295 DAC 5mg  China Supplier  CJC-1295 DAC has shown some amazing results as a hormone releasing hormone (GHRH) analog. Not only has CJC-1295 shown the ability to increase hormone and -I secretion and its benefits, but it has been able to do so in very large amounts. Recent research studies have shown that CJC - 1295 stimulates GH and IGF-1 Secretion, and will keep a steady increase of HGH and IGF-1 with no increase in prolactin, leading to intense fat loss, and increases protein synthesis.
  Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-LysLys(Maleimidopropionyl)-NH2 (Drug Affinity Complex) 
Molecular formula: C165H269N47O46
Molar Mass: 3647.15
CAS number: 863288-34-0
 ConjuChem and The Development of CJC-1295 DAC. CJC-1295 DAC is a tetrasubstituted peptide analogue of Hormone Releasing Hormones with D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 27 respectively. A Canadian biotechnology company called ConjuChem had invented CJC-1295. Clinical Research on CJC-1295 first began during the mid-2000s. The goal of the peptide, acting to raise likeIpamorelin, was to treat visceral fat deposits in obese AIDS patients because it is presumed that increased levels of exogenous increase fat loss, or lipolysis. In one study, results showed that the measured GH release in rats over a two hour period showed that CJC-1295 released twice as much GH as CJC-1293 DAC. This result makes it preferable for immediate effectiveness as a result of the longer peak. With the use of a Hormone Releasing Peptide (GHRP), such as Hormone Releasing Hexapeptide (GHRP-6) in conjuction with CJC-1295 DAC, a study has shown that the GHRP's create a Hormone pulse which helps the CJC-1295 work effectively. Clinical research's involving CJC-1295 have shown that it had been successful for most research subjects
C-1295 DAC is a long acting Hormone Releasing Hormone, which causes the anterior pituitary  to release more hormone. GHRH is released in pulses in the body, which alternate with corresponding pulses of somatostatin (growth-hormone inhibiting-hormone). The clinical research was ultimately successful for most research subjects. Ghrelin, released from the gut, which circulates and acts as a hunger hormone, has synergistic activity in the body with GHRH and also suppresses somatostatin to make way for the GHRH pulseThe DAC (Drug Affinity Complex) portion increases the half-life by binding with serum albumin and protects the CJC-1295 DAC peptide from degradation. This was formed when a lysine link was bounded to DACs to a reactive chemical called maleimidoproprionic acid (MPA).

CJC-1295 DAC vs. CJC-1295 No DAC
CJC-1295 DAC and CJC-1295 (also known as Modified GRF 1-29) are both Hormone Releasing Hormones (GHRH). Their action in the human body is identical but the difference between the two peptides are the span of the half-life. Modified GRF 1-29 and Sermorelin have a very short acting half-life of about 30 minutes, while CJC-1295 DAC has a half-life that can last up to approximately 8 days. Many a scientist have reported that the short half-life of Sermorelinand Modified GRF 1-29 is considered to be much more natural as they produce a short pulse of Human Hormone.
ConjuChem and The Development of CJC-1295 DAC
CJC-1295 DAC is a tetrasubstituted peptide analogue of Growth Hormone Releasing Hormones with D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 27 respectively. A Canadian biotechnology companyConjuChem had invented CJC-1295. Clinical Research on CJC-1295 first began during the mid-2000s. The goal of the peptide, acting to raise like Ipamorelin, was to treat visceral fat deposits in obese AIDS patients because it is presumed that increased levels of exogenous increase fat loss, or lipolysis. In one study, results showed that the measured GH release in rats over a two hour period showed that CJC-1295 released twice as much GH as CJC-1293 DAC. This result makes it preferable for immediate effectiveness as a result of the longer peak. With the use of a Hormone Releasing Peptide (GHRP), such as Hormone Releasing Hexapeptide (GHRP-6)in conjuction with CJC-1295 DAC, a study has shown that the GHRP's create a Hormone pulse which helps the CJC-1295 work effectively. Clinical research's involving CJC-1295 have shown that it had been successful for most research subjects.
Application & More information for CJC-1295 without DAC
 
Releasing Hormone (GHRH), which is the endogenously secreted GHRH by the arcuate nucleus of the hypothalamus of the human body, is 44 Amino Acids long. It was discovered, however, that only the first 29 amino acids of the protein were equally as effective in binding to receptors on the pituitary gland as the full 44 Amino Acid structure. The first 29 amino acids in its protein structure were then isolated, which was then called GRF 1-29, but the problem with this derivative of GHRH was the fact that it was rapidly metabolized and cleared from the body by enzymes. Studies have reported that GRF 1-29's half-life is less than 10 minutes and as little as 5 minutes. 
Therefore, the solution to this was to modify GRF 1-29 by replacing various amino acids in its structure with other amino acids that would provide a greater resistance to breakdown and cleavage by enzymes. There were many modified analogues developed, and Mod GRF 1-29 (CJC-1295 without DAC) was eventually selected for use, which demonstrated the most promising effects. Mod GRF 1-29 is a modification of GRF 1-29, specifically at amino acids #2, #8, #15, and #27. The result is an extended half-life to that of at least 30 minutes.

Mod GRF 1-29 acts upon receptors located in the anterior pituitary gland, and signals the pituitary gland to increase Human  production and cause a release of massive quantities of Human Hormone in a pulsatile manner.Therefore, multiple applications of Mod GRF 1-29 is recommended throughout the day in order to simulate Human Growth Hormone levels that remain high on a constant basis. Mod GRF 1-29 (CJC-1295 without DAC) is commonly combined with a Ghrelin mimetic (also known as a GHRP - Releasing Hexapeptide), such as GHRP-6, GHRP-2, Hexarelin, or Ipamorelin in order to initiate and amplify a greater pulse from the pituitary compared to Mod GRF 1-29 used solitarily on its own.

Our process:
The quality control process
1)Purchasing
Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.
2) Inspection
Four steps: sampling, sample pretreatment, measuring and data processing.
3) Producing
a)Each operator must do self-inspection of producs and make the corresponding inspection records.
b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.
4) Before selling
Test result can be provided before selling.
Third-party detection institution is allowed if you are not satisfied with test results.
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1. Quality:
Our company is a professional production of hormone intermediates for many years, our products have exported to Germany,Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, you can trust us.
And we are the manufactory, so no problem for us to control the quality.
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Sample Order :Package will be shipped with 3days after payment. We can send it via UP, EMS, HK Air Post, DHL or othermethod. We have a professional and stable logistics, and we can deliver the package smoothly around 3 to 5 days.

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